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MYP_046868
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Basic Information
Viscotoxin-B (Viscotoxin-B2) (VtB)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
46 amino acids
C197H328N64O67S6
Standard
Sequence
KSCCPNTTGRNIYNTCRLGGGSRERCASLSGCKIISASTCPSDYPK
Physicochemical Analysis
4857.49 Da
9.13
4.70
4.40
0.1022
-0.55
0.64
-0.16
46.52
46.74
0.0435
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2138.97
-33.49
83.0
78.0
158.0
334.0
5.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0134853 VERIFIED: YES
Provenance & Taxonomy
Viscum album [Plant]
plant thionin (TC 1.C.44) family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-40; 4-32; 16-26
Bio-Activity Profile
Toxin Venom plant thionin (TC 1.C.44) family Host defense
PaperPDB 2V9B structural record; X-ray; 1.05 A; chain A/B; residues 1-46
RECORD: Rec_0220777 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0295843 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID9348108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9348108/
RECORD: Rec_0379091 VERIFIED: YES
Provenance & Taxonomy
Viscum album [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal Cytotoxic
Sclerotinia sclerotiorum
PaperPubMed PMID: 1710983 | PubMed PMID: 12733989 PMID1710983;12733989 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1710983/
RECORD: Rec_0392843 VERIFIED: YES
Provenance & Taxonomy
Viscum album [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperIsolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album).
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