Peptide Database

Peptide NameSLAY-screened peptide P1115

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC40H61N13O15

DescriptionStandard

        DLLDAGSHH
    

Molecular Weight963.99 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.06

Net Charge (pH 7.4) -2.37

Charge Density (pH 7.0) -0.2293

GRAVY Index-0.58

Hydrophobic Moment 0.38

Boman Index0.05

Instability Index8.89

Aliphatic Index 97.78

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 448.31

LogP -5.11

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 30.0

Heavy Atoms 68.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249880 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/