Peptide Database

Peptide NameHill-Def 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC144H239N51O45S6

DescriptionStandard

        ATCTNWNCRTQCIARGKRGGYCVERNICKCTS
    

Molecular Weight3597.14 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.1480

GRAVY Index-0.58

Hydrophobic Moment 0.68

Boman Index-0.25

Instability Index39.03

Aliphatic Index 39.69

Aromaticity 0.0625

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1611.89

LogP -23.06

H-bond Donors 65.0

H-bond Acceptors 56.0

Rotatable Bonds 119.0

Heavy Atoms 246.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420742 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Tax ID343691

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa ATCC 9027

Activity32 μM

MethodIC50

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