Peptide Database

Peptide Name[D14A]GexIVA[1,2]

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC138H231N55O39S4

DescriptionStandard

        TCRSSGRYCRSPYARRRRYCRRITDACV
    

Molecular Weight3412.92 Da

Isoelectric Point (pI)10.77

Net Charge (pH 7.0)7.36

Net Charge (pH 7.4) 7.10

Charge Density (pH 7.0) 0.2627

GRAVY Index-1.12

Hydrophobic Moment 0.84

Boman Index-0.65

Instability Index161.50

Aliphatic Index 31.43

Aromaticity 0.1071

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1596.47

LogP -21.49

H-bond Donors 68.0

H-bond Acceptors 51.0

Rotatable Bonds 110.0

Heavy Atoms 236.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0014951 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyConotoxin

Tax ID32630

Structure & Mods

Configdisulfide-constrained linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-9; 20-27

Bio-Activity Profile

Function

Analgesic

Targetα9α10 nicotinic acetylcholine receptor

RECORD: Rec_0406471 VERIFIED: YES