Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC540H870N146O164S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNAGPTSIALTSCQTTSGDVDIKLNGKT
    

Molecular Weight12127.76 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.08

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index18.84

Aliphatic Index 97.46

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4936.80

LogP -55.25

H-bond Donors 174.0

H-bond Acceptors 172.0

Rotatable Bonds 399.0

Heavy Atoms 853.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072743 VERIFIED: NO

Provenance & Taxonomy

OrganismHypocryptadius cinnamomeus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria