Peptide Database

Peptide NameSarafotoxin S6 c

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H151N27O37S5

DescriptionStandard

        CTCNDMTDEECLNFCHQDVIW
    

Molecular Weight2519.78 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.18

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.2468

GRAVY Index-0.30

Hydrophobic Moment 0.34

Boman Index0.01

Instability Index86.83

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1046.02

LogP -10.82

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 80.0

Heavy Atoms 172.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140180 VERIFIED: NO

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0240795 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]

FamilySarafotoxin

Tax ID1343144

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour