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MYP_046802
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Basic Information
Brevinin-1BYa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C126H206N28O27S2
Standard
Sequence
FLPILASLAAKFGPKLFCLVTKKC
Physicochemical Analysis
2609.28 Da
9.70
3.74
3.50
0.1557
1.07
0.49
0.34
26.58
122.08
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
859.58
-2.34
31.0
33.0
84.0
183.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032379 VERIFIED: YES
Provenance & Taxonomy
Rana boylii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Streptococcus Group B HNTCC 80130
10 μM
MIC
PaperBrevinin-1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties
RECORD: Rec_0040051 VERIFIED: YES
Provenance & Taxonomy
Rana boylii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
human erythrocytes
4 μM
HC50
RECORD: Rec_0040731 VERIFIED: YES
Provenance & Taxonomy
Rana boylii [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
20.0 μM
MIC
PaperT. Pal et al. / International Journal of Antimicrobial Agents 27 (2006) 525-529. Brevinin-1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties Evidence URLhttps://www.uniprot.org/uniprotkb/P84111/entry
RECORD: Rec_0051707 VERIFIED: NO
Provenance & Taxonomy
American frog [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0053306 VERIFIED: YES
Provenance & Taxonomy
Rana boylii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Klebsiella pneumoniae KK3 9904
40 μM
MIC
PaperBrevinin-1BYa: a naturally occurring peptide from frog skin with broad-spectrum antibacterial and antifungal properties
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