Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC723H1135N195O207S14

DescriptionStandard

        MRTLLFTFAVFMLLVQLVSGNWYVKKCANKSGNCRMKCRSGEVETHPPTSKCPKTKVCCILPTSGYGGSCGAPKTTQMTGKTAVKTPSQGTTTAGSKDQERGICFIKMFRKGYYQTESKKYYFWEQYTNVLQLCFTAYGLRPPGDQ
    

Molecular Weight16319.84 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)13.49

Net Charge (pH 7.4) 13.05

Charge Density (pH 7.0) 0.0924

GRAVY Index-0.42

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index29.02

Aliphatic Index 52.05

Aromaticity 0.1164

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6500.46

LogP -69.85

H-bond Donors 237.0

H-bond Acceptors 236.0

Rotatable Bonds 536.0

Heavy Atoms 1139.0

Ring Count 28.0

Amide Bonds 157.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321289 VERIFIED: NO

Provenance & Taxonomy

OrganismOrycteropus afer afer [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin