Peptide Database

Peptide NameC-terminal Filaggrin-2 derived peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC114H160N34O40

DescriptionStandard

        HGLTQGLRHGSYGSADYDYGQSGYG
    

Molecular Weight2646.69 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.07

Net Charge (pH 7.4) -1.38

Charge Density (pH 7.0) -0.0427

GRAVY Index-1.06

Hydrophobic Moment 0.55

Boman Index-0.01

Instability Index23.76

Aliphatic Index 35.20

Aromaticity 0.1600

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1203.60

LogP -16.61

H-bond Donors 43.0

H-bond Acceptors 41.0

Rotatable Bonds 83.0

Heavy Atoms 188.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208604 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)