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MYP_046778
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Basic Information
Odorranain-F1 (OdF1; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C133H229N37O40S3
Standard
Sequence
GFMDTAKNAAKNVAVTLLDNLKCKITKAC
Physicochemical Analysis
3082.66 Da
9.24
2.74
2.50
0.0944
0.12
0.58
0.03
10.84
91.03
0.0345
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1272.78
-13.58
45.0
46.0
107.0
213.0
1.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0359645 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Brevinin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
8.40 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0368279 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Odorranain
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
8.4 μg/mL
MIC
PaperAnti-infection peptidomics of amphibian skin. Mol Cell Proteomics. 2007 May;6(5):882-94. doi: 10.1074/mcp.M600334-MCP200. PMID: 17272268. PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0389794 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Odorranain
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
1.05 μg/mL
MIC
PaperAnti-infection peptidomics of amphibian skin. Mol Cell Proteomics. 2007 May;6(5):882-94. doi: 10.1074/mcp.M600334-MCP200. PMID: 17272268. PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0406615 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Odorranain
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
23-29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
4.2 μg/mL
MIC
PaperAnti-infection peptidomics of amphibian skin. Mol Cell Proteomics. 2007 May;6(5):882-94. doi: 10.1074/mcp.M600334-MCP200. PMID: 17272268. PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
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