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MYP_046774
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Basic Information
Pep 2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C53H75N17O16S
Standard
Sequence
DRGWGNGCGLFG
Physicochemical Analysis
1238.33 Da
5.83
-0.25
-0.47
-0.0207
-0.44
0.43
0.13
-22.15
32.50
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
541.50
-6.56
20.0
17.0
38.0
87.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
DENV-4 | Vero cells
20 μM
% inhibition
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperIn vitro analysis of synthetic peptides in blocking the entry of dengue virus. | John AM, Jittmittraphap A, Chattanadee S, Alwin Prem Anand A, Shenbagarathai R, Leaungwutiwong P. | Virus Res. 2019 Jan 15;260:142-150. | DOI:10.1016/j.virusres.2018.11.016 | PMID:30508603 PMID30508603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508603/
RECORD: Rec_0364571 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
DENV-2 | Vero cells
10 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperIn vitro analysis of synthetic peptides in blocking the entry of dengue virus. | John AM, Jittmittraphap A, Chattanadee S, Alwin Prem Anand A, Shenbagarathai R, Leaungwutiwong P. | Virus Res. 2019 Jan 15;260:142-150. | DOI:10.1016/j.virusres.2018.11.016 | PMID:30508603 PMID30508603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508603/
RECORD: Rec_0415301 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
DENV-1:inhibition of virus infection in Vero cells(88%±3.89% inhibition at 50 μM
10 μM
IC50
PMID30508603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508603/
RECORD: Rec_0424104 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
DENV-2:inhibition of virus infection in Vero cells
10 μM
IC50
PMID30508603 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508603/
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