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MYP_046765
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
14 amino acids
C72H132N22O15
Standard
Sequence
RRKKPAVLLALLAP
Physicochemical Analysis
1545.96 Da
12.00
3.76
3.55
0.2684
0.34
0.20
-0.05
72.33
153.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
599.88
-2.60
21.0
19.0
50.0
109.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039279 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV Anti-Influenza
HSV, HIV, Influenza A Virus, H5 Avian Influenza Virus
PaperMethod of inhibiting influenza infection with antiviral peptides Evidence URLhttps://patents.google.com/patent/US7432045B2/en PatentUS 7432045 B2
RECORD: Rec_0182075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20050130884A1/en PatentUS 2005/0130884 A1
RECORD: Rec_0210369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Broad-spectrum antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV
HSV
PaperPharmacologically active antiviral peptides and methods of their use Evidence URLhttps://patents.google.com/patent/US20050130884/en PatentUS 20050130884
RECORD: Rec_0255535 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza virus Replication inhibition
Influenza virus | MDCK cells
10 μM
% inhibition
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 Apr;55(4):1810-3. | DOI:10.1128/AAC.01428-10 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
RECORD: Rec_0326942 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Signal peptide
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Influenza A virus (Virus entry); MDCK
96 %
Hemagglutinin assay
PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/
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