Peptide Database

Peptide NamekEA2x1 (Kallikrein inhibitor with external arginines)

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC84H138N32O28S3

DescriptionStandard

        ARCSDRFRNCPADEALCGR
    

Molecular Weight2140.39 Da

Isoelectric Point (pI)8.01

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.54

Charge Density (pH 7.0) 0.0406

GRAVY Index-0.81

Hydrophobic Moment 0.53

Boman Index-0.42

Instability Index26.29

Aliphatic Index 36.32

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1001.15

LogP -13.86

H-bond Donors 39.0

H-bond Acceptors 32.0

Rotatable Bonds 69.0

Heavy Atoms 147.0

Ring Count 2.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346153 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilykEA2x1

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery