Peptide Database

Peptide NameBeta-defensin 119 (Beta-defensin 120) (Defensin; beta 119) (Defensin; beta 120)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC443H700N116O123S9

DescriptionStandard

        MKLLYLFLAILLVIEEPVISGKRYILRCMGNSGICRASCKRNEQPYLYCKNYQSCCLQSYMRISISGKEENTDWSYEKQWPKLP
    

Molecular Weight9907.59 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0529

GRAVY Index-0.28

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index77.00

Aliphatic Index 88.21

Aromaticity 0.1190

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3896.18

LogP -30.74

H-bond Donors 142.0

H-bond Acceptors 137.0

Rotatable Bonds 331.0

Heavy Atoms 691.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035548 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic