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MYP_046714
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Basic Information
Apelin-17
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
17 amino acids
C96H156N34O20S
Standard
Sequence
KFRRQRPRLSHKGPMPF
Physicochemical Analysis
2138.55 Da
12.00
5.85
5.59
0.3438
-1.60
0.45
-0.57
103.01
22.94
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
894.19
-7.88
32.0
28.0
69.0
151.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0361143 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV Entry inhibition
HIV | NP-2/CD4/APJ cells
2.244 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperApelin peptides block the entry of human immunodeficiency virus (HIV). | Zou MX, Liu HY, Haraguchi Y, Soda Y, Tatemoto K, Hoshino H. | FEBS Lett. 2000 May 4;473(1):15-8. | DOI:10.1016/s0014-5793(00)01487-3 | PMID:10802050 PMID10802050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10802050/
RECORD: Rec_0387761 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV
PMID10802050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10802050/
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