Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length412 amino acids

Chemical FormulaC2043H3226N542O581S15

DescriptionStandard

        ELAQLKLPDMSGDSRVGNHCNMNFYSCIFRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLKAENVYIKISLRLGSNAAGKPTVSTSECSARISKVRVLFSGRLGYVTSLEGLELCGLSVSQICDIVDKSVQNELQTYVQTLPGTEGLPPLFAPLLHLSPSSQGEFYSLAHRSTVPFSPLPLALPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEDMIPKDVGFSLDTSLFSAFIPQVSSLALPAQSSCTHRLCSVPGISLNPIVEAQAYAILPNSSLAPLFLLSLVTTHLFFISHLSSSACTSPVPQTKAFPPLLPPPQVRTIQSLMNILTSKILLPRLNGENLLGRMWVLEHPTLRLLHPSGASSLIKSSLLRLIWGKSACRRLQ
    

Molecular Weight45157.73 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)4.83

Net Charge (pH 7.4) 3.85

Charge Density (pH 7.0) 0.0117

GRAVY Index0.18

Hydrophobic Moment 0.67

Boman Index0.14

Instability Index47.30

Aliphatic Index 103.42

Aromaticity 0.0850

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31900.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237965 VERIFIED: NO

Provenance & Taxonomy

OrganismCorvus moneduloides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria