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MYP_046674
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Basic Information
Hylaranin-L2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
16 amino acids
C79H135N21O19S
Standard
Sequence
GVLSVIKNALPGIMRF
Physicochemical Analysis
1715.11 Da
11.00
1.76
1.55
0.1099
1.02
0.70
0.35
6.09
140.00
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
642.27
-3.79
22.0
22.0
56.0
120.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095787 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0113089 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
34 μM
MIC
PaperHylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii.
RECORD: Rec_0149863 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
4-9 μM
MIC
PaperHylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii.
RECORD: Rec_0153593 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
4.3 μM
MIC
PaperHylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii.
RECORD: Rec_0310821 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24378871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24378871/
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