Peptide Database

Peptide NameDermaseptin DRS-DU-1

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC129H219N37O37S

DescriptionStandard

        ALWKSLLKNVGKAAGKAALNAVTDMVNQ
    

Molecular Weight2912.41 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.60

Charge Density (pH 7.0) 0.0998

GRAVY Index0.15

Hydrophobic Moment 0.66

Boman Index0.12

Instability Index0.25

Aliphatic Index 108.21

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1219.01

LogP -12.24

H-bond Donors 41.0

H-bond Acceptors 41.0

Rotatable Bonds 100.0

Heavy Atoms 204.0

Ring Count 2.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324519 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anticancer

TargetPseudomonas aeruginosa

Activity4 μM

MethodMIC

RECORD: Rec_0416537 VERIFIED: YES