Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC129H212N34O37S6

DescriptionStandard

        GIPCGESCVFIPCITAAIGCSCKTKVCYR
    

Molecular Weight3023.66 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0586

GRAVY Index0.80

Hydrophobic Moment 0.28

Boman Index0.24

Instability Index14.71

Aliphatic Index 80.69

Aromaticity 0.0690

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1112.93

LogP -11.68

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 94.0

Heavy Atoms 206.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324259 VERIFIED: YES

Provenance & Taxonomy

OrganismGloeospermum blakeanum [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)