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MYP_046614
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Basic Information
F25
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C119H186N32O26
Standard
Sequence
KKAAAFAAAAAFAAWAAFAAAKKKK
Physicochemical Analysis
2480.95 Da
10.70
5.75
5.54
0.2302
0.44
0.25
0.19
3.59
60.00
0.1600
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
933.63
-6.44
33.0
32.0
81.0
177.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis C621
2 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0078335 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. xerosis C875
0.25 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0080641 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12384369/ PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0096269 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0152617 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
1 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
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