Peptide Database

Peptide NameDrosophila defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC187H290N56O52S6

DescriptionStandard

        ATCDLLSKWNWNHTACAAHCIAKKYKGGYCNDKAVCVCR
    

Molecular Weight4347.04 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)3.91

Net Charge (pH 7.4) 3.52

Charge Density (pH 7.0) 0.1002

GRAVY Index-0.23

Hydrophobic Moment 0.39

Boman Index-0.03

Instability Index20.21

Aliphatic Index 60.26

Aromaticity 0.1026

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1755.08

LogP -18.25

H-bond Donors 68.0

H-bond Acceptors 64.0

Rotatable Bonds 140.0

Heavy Atoms 301.0

Ring Count 8.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273985 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila biarmipes [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)