Peptide Database

Peptide NameMHVWW-IV

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC110H138N22O34

DescriptionStandard

        GYFVQDDGEWKFTGSSYYY
    

Molecular Weight2312.40 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.1179

GRAVY Index-0.93

Hydrophobic Moment 0.13

Boman Index0.08

Instability Index21.92

Aliphatic Index 15.26

Aromaticity 0.3684

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 925.53

LogP -6.75

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 69.0

Heavy Atoms 166.0

Ring Count 8.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401559 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetMurine Hepatitis Virus (MHV/M-CoV)

Activity90-100 %

MethodInhibition

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