Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC166H253N43O49S7

DescriptionStandard

        DHYQCVKNGGFCLYSSCPMYSSIIGTCYKGKAKCC
    

Molecular Weight3859.50 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0795

GRAVY Index-0.09

Hydrophobic Moment 0.35

Boman Index0.07

Instability Index45.03

Aliphatic Index 44.57

Aromaticity 0.1429

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1482.24

LogP -16.46

H-bond Donors 58.0

H-bond Acceptors 60.0

Rotatable Bonds 124.0

Heavy Atoms 265.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302989 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)