Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length474 amino acids

Chemical FormulaC2330H3666N584O672S21

DescriptionStandard

        MMYLTLLILPCLAAVTLGSNPGIQVALTNKGLQYGARVGADLLQTKITTVPIPQVSGSVSLGPLGSVQYALSEMKVVKVNLPLPTVGFSEGTGVKADLSGLNIAVSGRWNTHYHIIRDGGTFDLAVFRIGTDSVVKLGSDSKGHLSVSSVQCSSSVGDIQISFHGGASFIFKSFVKYFKPEIQSKIQQNICPLFEESIQDVEKYLAGMKVSFQVTPTLLIDMPLVSPPMVQTSNLNLSFKGEFYDVKKHTEPPFVADPFQLPQQDGFMVSLGMSEFTLNSATFAYFSGGKFQINITDKMIPPESPIHLTTTSFGAFVPQLPQMYPNMQMLFHVYATETPMFSFLPDNVTLSLSASAKAYVIEQNSSLVPVFRLDTNASFSGRFLLEGGKLKGSLMLNNVTLTLGASEVGTFQTGTLQYMLRMAMNVAVLPKVNEKLKAGIPLPAIGHVQWVNSMLKVKKGFVAVATDANVSYEG
    

Molecular Weight51284.90 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)2.19

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0046

GRAVY Index0.20

Hydrophobic Moment 0.70

Boman Index0.20

Instability Index38.38

Aliphatic Index 94.32

Aromaticity 0.0928

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198458 VERIFIED: NO

Provenance & Taxonomy

OrganismAlbula glossodonta [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence