Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H872N146O165S3

DescriptionStandard

        PDLTGHEKFSLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNAGPTSISLSSCWTTSGDVDIKLNGKT
    

Molecular Weight12217.84 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.08

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index21.95

Aliphatic Index 96.58

Aromaticity 0.0702

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4949.96

LogP -54.84

H-bond Donors 176.0

H-bond Acceptors 173.0

Rotatable Bonds 400.0

Heavy Atoms 860.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423832 VERIFIED: NO

Provenance & Taxonomy

OrganismLeiothrix lutea (Red-billed leiothrix) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria