Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC396H639N107O105S10

DescriptionStandard

        MALEVCKHPVAMTQRLLLLVALLVLGHVPTGRSEFKRCWNGQGACRTYCTKYETYMHLCPDATLCCLPYGLKPVKTEKV
    

Molecular Weight8899.61 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.69

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0594

GRAVY Index0.12

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index53.60

Aliphatic Index 91.27

Aromaticity 0.0759

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3353.25

LogP -25.60

H-bond Donors 124.0

H-bond Acceptors 123.0

Rotatable Bonds 287.0

Heavy Atoms 618.0

Ring Count 15.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090964 VERIFIED: NO

Provenance & Taxonomy

OrganismCervus elaphus hippelaphus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

MethodQualitative functional evidence