Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length520 amino acids

Chemical FormulaC2515H4054N722O711S15

DescriptionStandard

        MTETGPAMAPAAPAPGGTATACHAPRSRSCPKAEGGLLAPRCPPRGSALALLCLLLLLAACSPATGSSPGIKGRVTQRALEYGRHFGLELLRSQLQKEHELNLQGSYRPPFLGEIQYSVPRIHIQELQMNDSSVDFAEDVGVRLAVQGARIQLSADWSAQLGTFQDSGVVRLRVADLAVAVVLGLSVDEGGRPAVWAAGCDARGTDLHLEFQRGQSWLYNLLVPLLQRALRQQLNKQLCVELEKSIGRLEASLKRMRVSPQLDPFAAIDLSLLGRPAITAEHGDVSLKGEFFGVGRRRQSPFSPKPVGLPEAREPMVLLALTEFVANSAAFVYFTAGALRRNISGEALPRRFPIQLRTKSLGGFSPQLQELFPDLPMELQLSARRQPLLSCRPDALHGTLYGSAEAFVVLPNATRVPAFLLDIDANVTGKPSITGNRLGGTVRLTSLSVAQVTSQVGPLQVKKLENVLKFGLWLFGVPWANKRLRSGVPLPTPRGLSLVHPRLSLHEGFMLLATDLQYEP
    

Molecular Weight56262.48 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)13.28

Net Charge (pH 7.4) 12.40

Charge Density (pH 7.0) 0.0255

GRAVY Index-0.01

Hydrophobic Moment 0.75

Boman Index0.06

Instability Index55.10

Aliphatic Index 99.83

Aromaticity 0.0615

Extinction Coeff. Reduced 37930.00

Extinction Coeff. Oxidized 38430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161001 VERIFIED: NO

Provenance & Taxonomy

OrganismCairina moschata domestica (Muscovy Duck (domestic type)) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria