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MYP_046443
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Basic Information
Defensin-6 (Defensin; alpha 6)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
100 amino acids
C470H743N135O153S8
Standard
Sequence
MRTLTILTAVLLVALQAKAEPLQAEDEPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL
Physicochemical Analysis
10989.26 Da
5.23
-3.37
-3.79
-0.0337
-0.17
0.57
-0.02
57.26
73.40
0.0800
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4666.26
-54.96
170.0
160.0
362.0
766.0
12.0
107.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043955 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Alpha-defensin; Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
L. acidophilus (Gram-positive)
PMID15494476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15494476/
RECORD: Rec_0043972 VERIFIED: NO
Provenance & Taxonomy
Pan paniscus [Animal]
Defensin
9597
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic
Qualitative functional evidence
Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22722832/
RECORD: Rec_0071747 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Alpha-defensin; Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID15494476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15494476/
RECORD: Rec_0160586 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Alpha-defensin; Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. thermophilus (Gram-positive)
PMID15494476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15494476/
RECORD: Rec_0166821 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Alpha-defensin; Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Y. enterocolitica (Gram-negative)
PMID15494476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15494476/
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