Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC742H1173N219O218S8

DescriptionStandard

        MAKVQFKPRSETTLLIVHCSATKPTMNIGLREIRQWHKERGWLDVGYHFIIRRDGTVEDGREVSAIGAHCEGKNYTSVGVCLVGGVNDKMQPEANFTPQQMESLKTLLAGLKREYPQASIHGHHDFAAKACPSFDVQRWLKSGELVTSDRG
    

Molecular Weight16906.11 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.09

Net Charge (pH 7.4) 2.42

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.47

Hydrophobic Moment 0.75

Boman Index-0.05

Instability Index41.31

Aliphatic Index 74.24

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7035.83

LogP -72.43

H-bond Donors 249.0

H-bond Acceptors 236.0

Rotatable Bonds 565.0

Heavy Atoms 1187.0

Ring Count 27.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086117 VERIFIED: YES

Provenance & Taxonomy

OrganismDickeya phage vB_DsoP_JA10 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic