Peptide Database

Peptide Name[D-Phe12]bombesin

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC74H113N21O20S

DescriptionStandard

        EQRLGNQWAVGFLM
    

Molecular Weight1648.88 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) -0.0117

GRAVY Index-0.14

Hydrophobic Moment 0.49

Boman Index0.12

Instability Index-5.21

Aliphatic Index 83.57

Aromaticity 0.1429

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 685.88

LogP -5.01

H-bond Donors 23.0

H-bond Acceptors 21.0

Rotatable Bonds 54.0

Heavy Atoms 116.0

Ring Count 3.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419844 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Neuropeptide activity Signaling peptide

TargetBB2 receptor (Rat)

Activity10000 nM

MethodKi