Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC543H887N165O143S11

DescriptionStandard

        MKLLLLVFASFGFLGTPASGGRARCTHKFPGRCKMSCNSLERSIFMCDRYKLCCVKDPLRTIAPPPVHKVQNRCRKTTKRQNEEHQMGIPPKPLSLPSIQHNYRTPIKG
    

Molecular Weight12367.59 Da

Isoelectric Point (pI)10.19

Net Charge (pH 7.0)14.78

Net Charge (pH 7.4) 14.23

Charge Density (pH 7.0) 0.1356

GRAVY Index-0.47

Hydrophobic Moment 0.62

Boman Index-0.13

Instability Index50.79

Aliphatic Index 67.98

Aromaticity 0.0642

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4938.02

LogP -50.10

H-bond Donors 178.0

H-bond Acceptors 173.0

Rotatable Bonds 407.0

Heavy Atoms 862.0

Ring Count 22.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038672 VERIFIED: NO

Provenance & Taxonomy

OrganismOdobenus rosmarus divergens [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0128627 VERIFIED: NO