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MYP_046269
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Basic Information
[E]7 -VmCT1-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C73H107N15O17
Standard
Sequence
FLGALWEVAKSVF
Physicochemical Analysis
1466.72 Da
6.00
-0.24
-0.44
-0.0183
1.21
0.44
0.52
20.92
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
511.86
-0.51
18.0
17.0
45.0
105.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0336229 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli SBS 363
12.5
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0349085 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans MDM8
12.5 μM
MIC
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0353268 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
12.5
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0365502 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus (A270)
1.56 μM
MIC
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0383407 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli (SBS 363)
1.56 μM
MIC
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
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