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MYP_046269
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Basic Information
[E]7 -VmCT1-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C73H107N15O17
Standard
Sequence
FLGALWEVAKSVF
Physicochemical Analysis
1466.72 Da
6.00
-0.24
-0.44
-0.0183
1.21
0.44
0.52
20.92
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
511.86
-0.51
18.0
17.0
45.0
105.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087872 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
0.78
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0097039 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli D31
12.5
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0121322 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis (ATCC 12228)
6.25 μM
MIC
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0130908 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans MDM8
12.5
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0151218 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
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