Peptide Database

Peptide NameSLAY-screened peptide P4059

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H153N25O28S

DescriptionStandard

        PTSIPVTSPHIVEPSCAPRL
    

Molecular Weight2101.43 Da

Isoelectric Point (pI)7.13

Net Charge (pH 7.0)0.04

Net Charge (pH 7.4) -0.09

Charge Density (pH 7.0) 0.0019

GRAVY Index0.12

Hydrophobic Moment 0.24

Boman Index0.16

Instability Index94.56

Aliphatic Index 92.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 796.10

LogP -8.71

H-bond Donors 28.0

H-bond Acceptors 30.0

Rotatable Bonds 58.0

Heavy Atoms 147.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139347 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/