Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC461H742N128O159S4

DescriptionStandard

        APGVTVTPATGLSNGQTVTVSATGLTPGTVYHVGQCAVVEPGVIGCDATTSTDVTADAAGKITAQLKVHSSFQAVVGANGTPWGTVNCKVVSCSAGLGSDSGEGAAQAITFA
    

Molecular Weight10749.84 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-3.06

Net Charge (pH 7.4) -3.42

Charge Density (pH 7.0) -0.0274

GRAVY Index0.34

Hydrophobic Moment 0.42

Boman Index0.26

Instability Index4.80

Aliphatic Index 80.09

Aromaticity 0.0357

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4495.18

LogP -66.22

H-bond Donors 158.0

H-bond Acceptors 162.0

Rotatable Bonds 336.0

Heavy Atoms 752.0

Ring Count 12.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288407 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces macromomyceticus [Bacterium]

Familyneocarzinostatin family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide36-46; 88-93

Bio-Activity Profile

Function

Antimicrobial neocarzinostatin family Antibacterial Host defense