Peptide Database

Peptide NameDEFB120

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC132H217N47O41S7

DescriptionStandard

        CWMGGYCRLVCQDNEDTISRCRSRKRCC
    

Molecular Weight3342.88 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0966

GRAVY Index-0.71

Hydrophobic Moment 0.48

Boman Index-0.39

Instability Index74.72

Aliphatic Index 38.21

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1479.33

LogP -18.73

H-bond Donors 61.0

H-bond Acceptors 51.0

Rotatable Bonds 112.0

Heavy Atoms 227.0

Ring Count 3.0

Amide Bonds 29.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0243748 VERIFIED: YES

Provenance & Taxonomy

OrganismElephantulus edwardii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)