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MYP_046207
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Basic Information
K1K8
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
14 amino acids
C80H133N19O16
Standard
Sequence
KILGKLWKGVKSIF
Physicochemical Analysis
1617.03 Da
10.48
3.76
3.55
0.2683
0.39
0.71
0.20
13.64
132.14
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
581.72
-0.72
21.0
20.0
57.0
115.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0237268 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0245257 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC25923
12.5 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0249553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Wound healing
Candida albicans ATCC 10231 or CMCC 98001 or AY 93025 and 5 clinical strains
15.5-62 μM
MIC
PaperK1K8: an Hp1404-derived antibacterial peptide.
RECORD: Rec_0253811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 6538
12.5 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0258549 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus MRSA P1374
6.25 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
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