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MYP_046207
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Basic Information
K1K8
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
14 amino acids
C80H133N19O16
Standard
Sequence
KILGKLWKGVKSIF
Physicochemical Analysis
1617.03 Da
10.48
3.76
3.55
0.2683
0.39
0.71
0.20
13.64
132.14
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
581.72
-0.72
21.0
20.0
57.0
115.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196890 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Wound healing
Pseudomonas aeruginosa AB93066 or ATCC9027
50 μg/mL
MIC
PaperK1K8: an Hp1404-derived antibacterial peptide.
RECORD: Rec_0200850 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HEK293T cell lines
Cell viability assay
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0216520 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa AB93066
50 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0228205 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
400 μg/mL
Hemolysis
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0229791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Wound healing
HFF
100-200 μg/mL
IC50
PaperK1K8: an Hp1404-derived antibacterial peptide.
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