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MYP_046207
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Basic Information
K1K8
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
14 amino acids
C80H133N19O16
Standard
Sequence
KILGKLWKGVKSIF
Physicochemical Analysis
1617.03 Da
10.48
3.76
3.55
0.2683
0.39
0.71
0.20
13.64
132.14
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
581.72
-0.72
21.0
20.0
57.0
115.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017089 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0033003 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli AB94012
25 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0045719 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
50 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0050965 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
50 μg/mL
MIC
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
RECORD: Rec_0100137 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
The cell vaibility of HFF cell lines is 100%, 108%, 105% and 38% at peptide concentrations of 0 μg/ml, 50 μg/ml, 100 μg/ml and 200 μg/ml
PMID26952110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952110/
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