Peptide Database

Peptide NameBeta-defensin 124 (Beta-defensin 24) (DEFB-24) (Defensin; beta 124)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC361H563N95O98S8

DescriptionStandard

        MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
    

Molecular Weight8058.43 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0241

GRAVY Index-0.05

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index70.77

Aliphatic Index 82.39

Aromaticity 0.0986

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3040.81

LogP -24.11

H-bond Donors 110.0

H-bond Acceptors 111.0

Rotatable Bonds 255.0

Heavy Atoms 562.0

Ring Count 17.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288667 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found