Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC568H882N162O172S10

DescriptionStandard

        MKLLTTIWRLKLEKMYSKTNTSSTIFEKAHGTEKISTARSEGHYIIFNRWKACIAIGGRCKNQCDDSEFRISYCERPTTHCCVRECDPMDPNNWIPKDSVGTQEWYPKDSSH
    

Molecular Weight13052.71 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.24

Charge Density (pH 7.0) 0.0250

GRAVY Index-0.78

Hydrophobic Moment 0.50

Boman Index-0.16

Instability Index43.60

Aliphatic Index 54.02

Aromaticity 0.0982

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5430.20

LogP -57.52

H-bond Donors 199.0

H-bond Acceptors 189.0

Rotatable Bonds 432.0

Heavy Atoms 912.0

Ring Count 24.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041919 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0132711 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyBeta-defensin; Defensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic