Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2338H3696N584O695S17

DescriptionStandard

        MVKICCSLLLLSLLSGQLSANPGLKVRITQKGLEYAKEVGLEILKQNMEKESFPDLTGHEKFGLGNVKYNISRIRVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLTSCQTTSGDIDIKLNGKSGFLHNFFIKYLKKPIHRSLVTNSCPNIRAGIQLIDEDLQSLNVAMQIDDLAEVDYSLSSLPAVFRPFIDLDLKGVAFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNITIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNVFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANAKLSKGFPLPNLANVTLTRPHITIVQGYVLISTDVHYKH
    

Molecular Weight51650.96 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-7.82

Net Charge (pH 7.4) -8.63

Charge Density (pH 7.0) -0.0166

GRAVY Index0.19

Hydrophobic Moment 0.77

Boman Index0.17

Instability Index36.92

Aliphatic Index 104.53

Aromaticity 0.0894

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33725.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204348 VERIFIED: NO

Provenance & Taxonomy

OrganismCorvus moneduloides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria