Peptide Database

Peptide NameDermaseptin PD-3-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC320H521N85O109S3

DescriptionStandard

        MSFMKKSLLLVLFLGVVSLSNCEEEKGENENEDHEEHHEEKRLLGDLLGQTSKLVNDLTDTVGSIV
    

Molecular Weight7399.26 Da

Isoelectric Point (pI)4.60

Net Charge (pH 7.0)-8.22

Net Charge (pH 7.4) -8.63

Charge Density (pH 7.0) -0.1246

GRAVY Index-0.33

Hydrophobic Moment 0.61

Boman Index-0.01

Instability Index33.98

Aliphatic Index 103.18

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3152.58

LogP -31.26

H-bond Donors 107.0

H-bond Acceptors 107.0

Rotatable Bonds 262.0

Heavy Atoms 517.0

Ring Count 5.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161548 VERIFIED: NO

Provenance & Taxonomy

OrganismAgalychnis dacnicolor [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence