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MYP_046097
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Basic Information
Rfamid
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
8 amino acids
C46H75N17O9
Standard
Sequence
KPHLRGRF
Physicochemical Analysis
1010.20 Da
12.00
2.85
2.59
0.3558
-1.44
0.07
-0.51
12.79
48.75
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
436.73
-3.16
16.0
13.0
32.0
72.0
3.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035613 VERIFIED: YES
Provenance & Taxonomy
Hydra [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter sp.
1.8 μM
MIC
PMID28951596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28951596/
RECORD: Rec_0045533 VERIFIED: YES
Provenance & Taxonomy
Hydra vulgaris [Animal]
Hydra-RFamide
6087
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
Mammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Hydra-RFamide 3 (Hydra vulgaris): PMID 8954943 PMID8954943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8954943/
RECORD: Rec_0054887 VERIFIED: YES
Provenance & Taxonomy
Hydra [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas sp.
58.2 μM
MIC
PMID28951596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28951596/
RECORD: Rec_0075310 VERIFIED: YES
Provenance & Taxonomy
Hydra vulgaris [Animal]
FMRFamide related peptide
6087
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID8954943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8954943/
RECORD: Rec_0191575 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
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