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MYP_046078
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Basic Information
NRC-127
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C127H204N36O29S
Standard
Sequence
GCKKWFKKAAHVGKNVGKVALNAYL
Physicochemical Analysis
2731.27 Da
10.14
5.83
5.55
0.2332
-0.17
0.65
0.03
-16.79
82.00
0.1200
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1068.72
-7.60
38.0
37.0
93.0
193.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006790 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0013785 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0149287 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HL-60 (50% Cell death=32 μg/ml)
PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0278445 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21729875/ PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0362136 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>256 μg/mL
Hemolysis
PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/