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MYP_046066
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Basic Information
Gramicidin A [l10,12,14r]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C96H138N28O16
Standard
Sequence
VGALAVVVWRWRWRW
Physicochemical Analysis
1940.30 Da
12.00
2.73
2.52
0.1823
0.45
0.36
0.18
112.57
116.67
0.2667
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
719.58
0.21
29.0
19.0
55.0
140.0
8.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012204 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at 20 microM
20 μM
Hemolysis
PMID22113881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22113881/
RECORD: Rec_0087371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 6633
2.5-5 μM
MIC
PMID22113881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22113881/
RECORD: Rec_0117704 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538
10 μM
MIC
PMID22113881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22113881/
RECORD: Rec_0208337 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pyogenes ATCC 19615
0.62 μM
MIC
PMID22113881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22113881/
RECORD: Rec_0223373 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538
2.5-5 μM
IC50
PMID22113881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22113881/
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