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MYP_046060
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Basic Information
Hymenoptaecin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
93 amino acids
C458H702N136O135S
Standard
Sequence
EFRGSIVIQGTKEGKSRPSLDIDYKQRVYDKNGMTGDAYGGLNIRPGQPSRQHAGFEFGKEYKNGFIKGQSEVQRGPGGRLSPYFGINGGFRF
Physicochemical Analysis
10305.37 Da
9.85
5.93
5.68
0.0637
-0.91
0.54
-0.13
34.85
49.25
0.1290
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4432.18
-50.48
153.0
143.0
347.0
730.0
18.0
102.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0280781 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
19%. Chemical modification: A 2-pyrrolidone-5-carboxylic acid was found at the N-terminus
Bio-Activity Profile
Antimicrobial
E. carotouoru ssp
1-5 μM
MIC
PaperFunctional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee (Apis mellifera).
RECORD: Rec_0302760 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
19%. Chemical modification: A 2-pyrrolidone-5-carboxylic acid was found at the N-terminus
Bio-Activity Profile
Antimicrobial
X. campestris
0.5-1.0 μM
MIC
PaperFunctional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee (Apis mellifera).
RECORD: Rec_0328395 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
19%. Chemical modification: A 2-pyrrolidone-5-carboxylic acid was found at the N-terminus
Bio-Activity Profile
Antimicrobial
G+ bacteria B. negaterium
0.5-1 μM
MIC
PaperFunctional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee (Apis mellifera).
RECORD: Rec_0342191 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Defensin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Haemophilus influenzae
PMID8463238 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8463238/
RECORD: Rec_0367459 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Defensin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bordetella bronchiseptica
PMID8463238 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8463238/
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