‹ ›
MYP_046050
← PREVIOUS NEXT → BACK
Basic Information
PAM2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
22 amino acids
C112H179N37O30
Standard
Sequence
RPWAGNGSVHRYTVLSPRLKTQ
Physicochemical Analysis
2523.85 Da
11.72
3.85
3.59
0.1748
-0.86
0.45
-0.20
1.44
66.36
0.0909
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1100.36
-12.28
40.0
35.0
78.0
179.0
6.0
23.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0220996 VERIFIED: YES
Provenance & Taxonomy
Ornithorhynchus anatinus [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
2.42 μM
MIC
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0226213 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0252012 VERIFIED: YES
Provenance & Taxonomy
Ornithorhynchus anatinus [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella enterica ATCC 14028
1.11 μM
MIC
PMID21912615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21912615/
RECORD: Rec_0290164 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 59.1%, C 40.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0298369 VERIFIED: YES
Provenance & Taxonomy
Ornithorhynchus anatinus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli DH5alpha
0.87 μM
MIC
PaperAncient antimicrobial peptides kill antibiotic-resistant pathogens: Australian mammals provide new options
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4