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MYP_046020
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Basic Information
Tyrocidine A1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C67H91N13O14
Standard
Sequence
FPFFNQYVKL
Physicochemical Analysis
1302.52 Da
8.59
0.76
0.55
0.0758
0.26
0.44
0.30
21.07
68.00
0.4000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
448.86
-0.08
14.0
15.0
38.0
94.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0220605 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID17462586 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0247732 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Listeria monocytogenes B73
38.0
MIC
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0259104 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Plasmodium falciparum 3D7
0.0044 μM
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0264130 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
12.0 μM
LC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0278645 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Micrococcus luteus NCTC 8340
26.0
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
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