Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC481H783N125O130S7

DescriptionStandard

        MKLFLVLTILLFEVLTDGARLKKCFNNVTGYCRKKCKVGEIHEIGCLSGKLCCVNDEENKKHVPFKKPHQQPVEKLSVQQDYVILPTITIFTV
    

Molecular Weight10621.58 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.0506

GRAVY Index0.02

Hydrophobic Moment 0.62

Boman Index0.05

Instability Index30.10

Aliphatic Index 103.55

Aromaticity 0.0753

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4110.16

LogP -30.59

H-bond Donors 144.0

H-bond Acceptors 145.0

Rotatable Bonds 362.0

Heavy Atoms 743.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268214 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence